Understanding Xtandi Prescribing Information: A Comprehensive Guide for Healthcare Providers
Introduction
Xtandi (enzalutamide) is a medication used to treat prostate cancer. It has been proven to be effective in delaying the progression of the disease, while also providing patients with a better quality of life. As a healthcare provider, it is essential to fully understand the prescribing information of Xtandi to ensure that you are providing the best possible care for your patients.
Body
1. What is Xtandi and How Does it Work?
Xtandi is an androgen receptor inhibitor that works by blocking the binding of androgens (male hormones) to the cancer cells, thus preventing their growth. It was approved by the FDA in 2012 and is currently used to treat metastatic castration-resistant prostate cancer.
2. Dosage and Administration
Xtandi is administered orally in the form of a capsule. The recommended dose is 160 mg once daily with or without food. It is important to note that the capsules should not be crushed, chewed or opened as this may increase the risk of exposure to the medication.
3. Side Effects
As with any medication, Xtandi may cause side effects, which should be closely monitored. The most common side effects include fatigue, hot flashes, hypertension, musculoskeletal pain, and diarrhea. It is essential to inform your patients of these potential side effects and encourage them to report any symptoms they may experience.
4. Drug Interactions
Xtandi may interact with other medications, including blood thinners, anti-seizure medications, and certain antibiotics. It is important to check for potential interactions before prescribing Xtandi to a patient.
5. Safety Information
Xtandi is not recommended for use in women who are pregnant or breastfeeding. It is also contraindicated in patients with a history of seizures or who have a known hypersensitivity to enzalutamide or any of its ingredients. It is essential to review the complete prescribing information before prescribing Xtandi to a patient.
Conclusion
In conclusion, understanding Xtandi’s prescribing information is crucial for healthcare providers to ensure the safe and effective treatment of prostate cancer. Proper dosage and administration, potential side effects, drug interactions, and safety information should be closely monitored to provide the best possible care for patients. By being knowledgeable about this medication, healthcare providers can ensure that their patients receive the best possible outcomes.
References:
– Xtandi Prescribing Information. (2021). Retrieved from https://www.astellas.us/docs/xtandi.pdf
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