Understanding Xeljanz Prescribing Information: Dosage, Side Effects, and Warnings
Xeljanz (tofacitinib) is a medication used to treat moderate to severe rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It works by blocking the action of certain enzymes that cause inflammation and therefore reduces swelling, pain, and stiffness. If you’re considering taking Xeljanz, it’s important to understand its prescribing information, including the dosage, side effects, and warnings.
Dosage
The usual dose of Xeljanz is one tablet (5mg) twice a day for rheumatoid arthritis and psoriatic arthritis. For ulcerative colitis, the initial dose is two tablets (10mg) twice a day for the first eight weeks, followed by one tablet (5mg) twice a day. Your doctor will determine the appropriate dose based on your condition and response to treatment.
Side Effects
Xeljanz can cause several side effects, including infections, elevated cholesterol and liver enzymes, and an increased risk of certain cancers such as lymphoma and skin cancer. In addition, it can also increase your risk of blood clots, which can cause a heart attack or stroke.
Other possible side effects include:
– Diarrhea
– Headache
– Nausea
– Upper respiratory tract infections
– Nasal congestion
It’s important to contact your doctor immediately if you experience any of these side effects, especially if they’re severe or persistent.
Warnings
Xeljanz comes with several warnings and precautions that you need to consider before starting treatment. First, it’s not recommended for people with severe liver or kidney disease. Second, it’s important to get screened for tuberculosis (TB) before starting Xeljanz because it can worsen active TB or cause new TB infections.
Furthermore, Xeljanz can weaken your immune system, which makes you more vulnerable to infections. Therefore, you should avoid close contact with people who have contagious diseases such as the flu, chickenpox, or shingles. In addition, you should not receive any live vaccines while taking Xeljanz.
Conclusion
Xeljanz is an effective medication for treating rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. However, it’s important to understand its prescribing information, including the dosage, side effects, and warnings. If you’re considering taking Xeljanz, discuss it with your doctor and make an informed decision. Remember to contact your doctor immediately if you experience any side effects or have any concerns about the medication.
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