Understanding Trodelvy Prescribing Information: What You Need to Know
As of April 2021, Trodelvy received FDA approval for the treatment of metastatic triple-negative breast cancer and advanced urothelial cancer. The prescription medication produced by Immunomedics is a widely sought-after form of cancer treatment that harnesses the power of an antibody-drug conjugate called sacituzumab govitecan.
If you or a loved one has been recently diagnosed with either of these forms of cancer, you might have been advised to explore Trodelvy in association with your treatment plan. This article unpacks the essential elements of Trodelvy prescribing information and what you should know before starting the medication.
What is Trodelvy, and How Does it Work?
Trodelvy is a medication that targets cancer cells with increased specificity because it’s an antibody-drug conjugate. Its precise definition is a tumor-targeting antibody linked to an anticancer medication called a payload (SN-38). The antibody affixes to cells expressing a specific protein called TROP-2, which is often present in numerous types of cancers, including breast, bladder, lung, and triple-negative breast cancer.
Once the antibody upon drinking and binding the TROP-2 protein, it transports the SN-38 payload inside the cancer cells. Then, the drug is released and attacks the cancer cells from within. This kind of deployment of the drug directly eliminates the cancer cells while leaving healthy cells intact, reducing the chance of adverse effects on healthy cells.
Understanding the Right Dosage
Trodelvy dosages depend on the type of cancer, height, weight, body mass index (BMI), medication history, and kidney function of the patient. The medication comes in 100mg and 180mg vials, and in some instances, your oncologist may advise adjusting the dosage of your medication as the treatment progresses.
Patients with mild to moderate liver or kidney impairment and who are on chemotherapy might require dose reduction or adjustment. It’s always best to consult with a medical professional before beginning any medication.
Possible Side Effects of Trodelvy
As with any medication, Trodelvy has its side effects. The good news is that the majority of side effects are non-life-threatening and are managed using medications, hydration, and pre-medicating to prevent severe reactions. However, some patients may experience adverse events that could require discontinuation of the medication.
Some common side effects include:
– Diarrhea
– Nausea
– Anemia
– Fatigue
– Low platelet or white blood cell count
– Hair loss
– Skin rash
– Loss of appetite
Final Thoughts
Trodelvy has the potential to improve the lives of many cancer patients who have limited treatment options. Understanding the various aspects of Trodelvy’s prescribing information is essential for patients, caregivers, and medical professionals.
As is always the case, before initiating any medication or medical procedure, it’s critical to keep open communication with your medical professional. We hope this article has provided you with valuable information on Trodelvy prescribing information and the importance of making well-informed medical decisions.
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