Understanding the Essential Elements of Tecfidera Prescribing Information
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that affects millions of people worldwide. Tecfidera (dimethyl fumarate) is a medication used to treat relapsing-remitting MS, and it’s essential to understand its prescribing information before taking it.
What is Tecfidera?
Tecfidera is an oral medication that reduces inflammation and prevents the immune system from attacking the central nervous system. It’s usually prescribed to patients who have had at least one relapse in the past two years or those who have evidence of disease activity on their MRI.
How does Tecfidera work?
Tecfidera works by activating a pathway called the Nrf2 pathway, which leads to an increase in the production of antioxidants that help protect nerve cells in the brain and spinal cord. It also suppresses the activation of immune cells that contribute to the inflammation and destruction of nerve cells in MS.
What are the side effects of Tecfidera?
The most common side effects of Tecfidera include flushing, stomach upset, nausea, and diarrhea. These side effects typically resolve within a few weeks of starting Tecfidera. However, some patients may experience more severe side effects, such as allergic reactions, liver damage, and a decrease in white blood cell count. Patients should discuss any concerns with their doctor.
Who should not take Tecfidera?
Patients who are allergic to dimethyl fumarate or any of the other ingredients in Tecfidera should not take it. Additionally, patients with severe liver disease or a history of low white blood cell count should avoid Tecfidera.
What precautions should be taken while taking Tecfidera?
Patients taking Tecfidera should be monitored for signs of infection and liver function regularly. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the risks and benefits of Tecfidera with their doctor. Patients should also notify their doctor of all other medications and supplements they are taking.
Conclusion
Tecfidera is an essential medication for the treatment of relapsing-remitting MS. It’s crucial for patients to understand its prescribing information before taking it to make informed decisions about their health. Patients should discuss any concerns they may have with their doctor to ensure they receive the best possible care.
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