Understanding Carvykti Prescribing Information: A Guide for Patients
If you are prescribed a new medication, it is important to understand its prescribing information to ensure safe and effective use. This is especially true for medications that treat complex conditions such as cancer. One such medication is Carvykti (capmatinib), a precision medicine used to treat patients with non-small cell lung cancer. Understanding Carvykti prescribing information is crucial for patients to get the most out of this medication while minimizing risks.
What is Carvykti?
Carvykti is a prescription medicine that targets a specific genetic mutation called MET exon 14 skipping. This mutation is found in about 3% to 4% of non-small cell lung cancer patients. It works by blocking the signaling pathway that promotes tumor growth, leading to cell death. Carvykti is approved by the US Food and Drug Administration (FDA) for the treatment of advanced or metastatic non-small cell lung cancer that has tested positive for MET exon 14 skipping.
How is Carvykti Prescribed?
Carvykti is available as a tablet in two strengths, 150 mg and 200 mg. The recommended dose is 400 mg once daily for patients who weigh more than 50 kg. Patients with severe liver impairment or moderate-to-severe renal impairment may require dose adjustments. Carvykti should be taken on an empty stomach, at least one hour before or two hours after a meal.
What are the Possible Side Effects of Carvykti?
As with any medication, Carvykti can cause side effects, some of which may be serious. The most common side effects reported in clinical trials include peripheral edema, nausea, vomiting, fatigue, and decreased appetite. More serious side effects, although rare, may include interstitial lung disease, hepatotoxicity, and eye disorders. Patients should report any unusual symptoms to their healthcare provider immediately.
What Precautions Should Patients Take When Using Carvykti?
Patients should inform their healthcare provider if they are pregnant or breastfeeding, as the safety of Carvykti in pregnancy and lactation has not been established. Patients should also inform their healthcare provider of all medications, supplements, and herbal products they are taking, as some may interact with Carvykti and increase the risk of side effects. Patients should avoid driving or operating heavy machinery if they feel dizzy or lightheaded while taking Carvykti.
Conclusion
Understanding Carvykti prescribing information is crucial for patients to get the best possible outcomes while minimizing risks. Patients should carefully read the medication guide and ask their healthcare provider any questions they have. With the right information and precautions, patients can use Carvykti safely and effectively for their non-small cell lung cancer treatment.
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