Understanding Addyi Prescribing Information: A Guide for Patients
Addyi, also known by its generic name Flibanserin, is a medication used to treat a type of sexual dysfunction called Hypoactive Sexual Desire Disorder (HSDD) that affects women. This condition is characterized by low sexual desire, which causes distress or interpersonal difficulties for the individual. Addyi works by increasing the amount of neurotransmitters that stimulate sexual desire in the brain. However, it’s important to note that it is not a “female Viagra” and does not work instantly like Viagra does for men. In this article, we’ll take an in-depth look at the prescribing information for Addyi, its uses, side-effects, dosages, and a few things to keep in mind before taking it.
What is Hypoactive Sexual Desire Disorder (HSDD)?
HSDD is a sexual health disorder that affects women, involving low sexual desire, arousal, and interest. It is different from sexual dysfunction (e.g., dyspareunia or vaginismus) which is related to pain, discomfort, or difficulty during sexual activities. HSDD, on the other hand, involves low desire or interest in sexual activities. HSDD can cause significant distress or relationship difficulties.
What is Addyi?
Addyi, also known as Flibanserin, is an FDA-approved medication for the treatment of HSDD in premenopausal women. It is not approved for postmenopausal women or men, and its efficacy in treating HSDD in these groups is not established. Addyi is classified as a serotonin receptor agonist and antagonist, which means it works by stimulating the neurotransmitters that regulate sexual desire.
How does Addyi work?
While the exact mechanism of action of Addyi remains unknown, it is believed to work by increasing the levels of dopamine and norepinephrine, neurotransmitters responsible for sexual response. Dopamine, in particular, plays a crucial role in sexual desire and reward-seeking behavior. Addyi stimulates the release of dopamine, thereby increasing sexual desire and arousal in women.
How is Addyi prescribed?
Addyi is prescribed orally as a 100mg tablet taken once daily at bedtime. It should not be taken during the day or with alcohol, as it can cause severe hypotension (low blood pressure), fainting, and dizziness. Women taking Addyi must abstain from drinking alcohol for at least two hours before and after taking the medication. The prescribing physician may increase or decrease the dose based on the patient’s response and tolerance to the medication.
What are the side effects of Addyi?
Common side effects of Addyi include dizziness, somnolence (drowsiness), nausea, fatigue, insomnia, and dry mouth. Approximately 10% of women may experience adverse effects such as headache, flushing, upper respiratory tract infection, and anxiety. More severe side effects can occur if Addyi is taken with alcohol, including low blood pressure, syncope (fainting), and central nervous system depression.
What should patients keep in mind before taking Addyi?
It’s important for patients to understand that Addyi is not a quick-fix solution for low sexual desire but rather requires consistent use over time to achieve its maximum efficacy. Additionally, it cannot be taken with alcohol and may cause drowsiness, so it’s important to avoid driving or operating machinery after taking it. Patients with liver or kidney dysfunction should use Addyi with caution, and its use during pregnancy or breastfeeding is not recommended.
Conclusion
If you’re a premenopausal woman dealing with HSDD, Addyi might be the solution you’ve been looking for. While it’s important to keep in mind that there is no quick-fix solution for HSDD, with consistent use, Addyi has shown efficacy in increasing sexual desire and improving the sexual health of women. However, it’s important to understand the medication’s prescribing information, side effects, dosages, and contraindications before taking it. Always consult with your healthcare provider before taking any medication for sexual dysfunction.
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