Uncovering the Common Symptoms of Zollinger Ellison Syndrome

Uncovering the Common Symptoms of Zollinger Ellison Syndrome

Zollinger Ellison Syndrome (ZES) is a rare condition that affects the pancreas and increases the production of stomach acid. This results in the development of ulcers in the stomach, intestine and other parts of the digestive system. In this article, we will look at the common symptoms of Zollinger Ellison Syndrome and how it can be diagnosed and treated.

Symptoms of Zollinger Ellison Syndrome

The symptoms of ZES are often mistaken for other gastrointestinal conditions such as acid reflux, peptic ulcers, and gastritis. However, the symptoms of ZES are usually more severe and persistent. The most common signs and symptoms of ZES include:

• Abdominal pain
• Diarrhea
• Nausea
• Heartburn
• Vomiting

These symptoms may occur frequently and can be difficult to manage, especially if the underlying cause is not diagnosed.

Diagnosis of Zollinger Ellison Syndrome

Diagnosing ZES requires a series of tests that evaluate the functioning of the digestive system. The first step in the diagnosis is to perform a blood test that measures the level of gastrin in the blood. Gastrin is a hormone that stimulates the production of stomach acid. In people with ZES, the level of gastrin in the blood is significantly higher than normal.

Another test that can be conducted is the secretin stimulation test. During this test, a hormone called secretin is injected into the body to stimulate the production of gastrin. If the levels of gastrin in the blood increase in response to secretin, it indicates the presence of ZES.

Treatment of Zollinger Ellison Syndrome

The treatment of ZES involves reducing the production of stomach acid. The first line of treatment is to prescribe proton pump inhibitors (PPIs) such as omeprazole or lanzoprazole, which can effectively lower the amount of acid produced by the stomach.

In certain cases, surgery might be necessary to remove tumors from the pancreas that are causing an overproduction of gastrin. This can be done through minimally invasive laparoscopic surgery or an open operation.

Conclusion

Zollinger Ellison Syndrome is a rare condition that affects the pancreas and results in the overproduction of stomach acid. The most common symptoms of ZES include abdominal pain, diarrhea, nausea, heartburn, and vomiting. If left untreated, ZES can lead to complications such as ulcers, bleeding, and even cancer. It is important to seek medical attention if you are experiencing persistent gastrointestinal symptoms. With appropriate diagnosis and treatment, people with ZES can manage their symptoms and lead a healthy life.