Xeljanz is a medication that is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It is important for patients and healthcare providers to have a comprehensive understanding of the drug’s prescribing information in order to make informed decisions about its use. This article aims to provide a detailed guide on interpreting the Xeljanz Prescribing Information.
Introduction
Xeljanz is a medication that has been approved by the U.S. Food and Drug Administration (FDA) to treat several conditions. It is important to read and understand the Prescribing Information before using the medication. The Prescribing Information contains critical information on the drug’s indications, dosage, side effects, drug interactions, and contraindications. In this article, we will provide a comprehensive guide to interpreting the Xeljanz Prescribing Information.
Body
Indications: The Prescribing Information states that Xeljanz is approved to treat adult patients with rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It is important to note that Xeljanz is not currently approved for any pediatric patients. Additionally, the drug is only approved for use in adults who have not responded well to other treatment options.
Dosage: The recommended dosage of Xeljanz varies depending on the condition being treated. For rheumatoid arthritis and psoriatic arthritis, the recommended starting dose is 5 mg twice daily. However, for patients with ulcerative colitis, the recommended starting dose is 10 mg twice daily. It is important to note that the maximum recommended dose for all conditions is 10 mg twice daily.
Side effects: Xeljanz can cause a range of side effects, ranging from mild to severe. The most common side effects include upper respiratory tract infections, headache, diarrhea, and nausea. Additionally, Xeljanz can increase the risk of serious infections, lymphoma, and other malignancies. Patients should be monitored closely for signs of infection while taking Xeljanz.
Drug interactions: Xeljanz can interact with other medications, including immunosuppressants and live vaccines. In particular, Xeljanz should not be used with biologic DMARDs or potent immunosuppressants. Patients should inform their healthcare provider if they are taking any other medications before starting Xeljanz.
Contraindications: Xeljanz is contraindicated in patients with a history of serious hypersensitivity reactions to the drug. Additionally, Xeljanz should not be used in patients who have an active, serious infection.
Conclusion
Understanding the Xeljanz Prescribing Information is critical for patients and healthcare providers. The Prescribing Information provides essential information on the indications, dosage, side effects, drug interactions, and contraindications of the drug. Patients should be educated on the risks and benefits of the medication before starting treatment. As with any medication, patients should speak with their healthcare provider to determine if Xeljanz is the right treatment option for them.
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