Xyrem Prescribing Information is an essential resource for healthcare professionals who prescribe Xyrem medication for patients. Xyrem, also called sodium oxybate, is a central nervous system depressant used to treat narcolepsy with cataplexy. Xyrem is a controlled substance due to its potential for misuse and abuse, which is why it requires strict adherence to Xyrem Prescribing Information. Let’s explore everything you need to know about Xyrem Prescribing Information.
What is Xyrem?
Xyrem is a medication that reduces excessive daytime sleepiness and cataplexy episodes in people with narcolepsy. The active ingredient in Xyrem is sodium oxybate, which is a form of gamma-hydroxybutyrate (GHB) that occurs naturally in the brain. Xyrem is a Schedule III controlled substance because of its potential for dependence, addiction, and abuse. Xyrem is only available to patients through the Xyrem Risk Evaluation and Mitigation Strategy (REMS) Program.
What is Xyrem Prescribing Information?
Xyrem Prescribing Information is a document created by the manufacturer of Xyrem, Jazz Pharmaceuticals, to provide healthcare professionals with all the necessary information on how to safely and effectively prescribe Xyrem. Xyrem Prescribing Information contains detailed instructions on how to dose Xyrem, how to titrate Xyrem, how to administer Xyrem, how to monitor patients on Xyrem, and how to manage adverse reactions to Xyrem.
Dosage and Administration
Xyrem is a liquid medication that is taken orally twice a night, at bedtime and then 2.5 to 4 hours later. Xyrem should only be dosed using the Xyrem measuring device provided. The initial dose of Xyrem is 2.25 grams per night and should be titrated up as needed to a maximum dose of 9 grams per night. The titration should be done in 0.75-gram increments every 1 to 2 weeks until the desired benefit is achieved.
Monitoring and Managing Adverse Reactions
Patients on Xyrem should be closely monitored for adverse reactions such as respiratory depression, bradycardia, or seizures. Xyrem should be discontinued if any of these adverse reactions occur. Xyrem is contraindicated in patients with severe respiratory insufficiency, respiratory depression, or hypersensitivity to sodium oxybate or any of its components.
Conclusion
Xyrem Prescribing Information is a valuable resource for healthcare professionals who prescribe Xyrem medication for patients with narcolepsy. Xyrem Prescribing Information provides detailed information on the dosing, administration, monitoring, and management of adverse reactions associated with Xyrem. It is important for healthcare professionals to adhere to Xyrem Prescribing Information to ensure safe and effective use of Xyrem for the treatment of narcolepsy.
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