As healthcare professionals, staying up-to-date with the latest prescribing information is of utmost importance. One medication that has gained attention in recent years is Spevigo. In this article, we will dive into everything you need to know about Spevigo prescribing information.
What is Spevigo?
Spevigo (risdiplam) is a prescription medication used to treat a rare genetic disorder called spinal muscular atrophy (SMA). This condition affects the nerve cells responsible for controlling muscle movement, causing muscle weakness and atrophy. Spevigo works by increasing the levels of a protein called survival of motor neuron (SMN) which is necessary for the normal functioning of these nerve cells.
Who can take Spevigo?
Spevigo is approved for use in patients aged 2 months and older with SMA. It is available in oral suspension form and is taken once daily.
What are the dosing recommendations for Spevigo?
The recommended starting dose of Spevigo is based on the weight of the patient. For patients weighing less than or equal to 21 kg, the starting dose is 0.2 mg/kg once daily. For patients weighing greater than 21 kg, the starting dose is 5 mg once daily. The dose may be adjusted based on the patient’s weight and response to treatment.
What are the possible side effects of Spevigo?
Like all medications, Spevigo can cause side effects. The most common side effects include fever, diarrhea, rash, and vomiting. These side effects are usually mild to moderate in severity and go away on their own. More serious side effects, such as liver problems and bleeding, are rare but may occur.
What precautions should be taken when prescribing Spevigo?
Before prescribing Spevigo, healthcare professionals should perform a thorough evaluation of the patient’s medical history and current medications. They should also monitor the patient for any signs of liver problems, bleeding, or respiratory infections.
In addition, healthcare professionals should inform their patients of the potential benefits and risks associated with Spevigo. Patients should be advised to report any new symptoms or side effects to their healthcare provider.
Conclusion
Spevigo is an important medication used to treat SMA, a rare genetic disorder that affects muscle movement. Healthcare professionals should be familiar with the dosing recommendations, possible side effects, and precautions associated with prescribing Spevigo. By staying up-to-date with the latest prescribing information, healthcare professionals can ensure that their patients receive the best possible care.
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