Breaking News: Artificial Intelligence Yields New Antibiotic
Artificial Intelligence (AI) has been making strides in different areas of our lives, from entertainment to healthcare, education to finance, and more. Now, it’s one step closer to changing the game in the field of medicine.
What Happened?
A team of researchers at MIT used a deep learning algorithm to sift through more than 100 million chemical compounds in search of a molecule that could combat antibiotic-resistant bacteria.
The algorithm analyzed the molecular structures of compounds already known to have antibiotic properties and used that information to identify chemical structures that theoretically could be antibiotic. Then, the algorithm highlighted those that could potentially be toxic or ineffective and quickly narrowed down the options.
The produced result was one molecule, halicin, which was tested against a variety of bacteria including carbapenem-resistant Enterobacteriaceae (CRE), one of the biggest threats to human health according to the World Health Organization (WHO).
What’s So Significant?
This process stands out against traditional drug discovery in several ways. Typically, finding a new antibiotic could take a decade or more and cost billions of dollars, and most discovered molecules fail in clinical trials.
However, this AI process took just a few years to produce a viable candidate. Not only could this groundbreaking technique save time and money, but it could result in new drugs to fight the increasing number of antibiotic-resistant bacteria.
What’s Next?
The road to clinical applications is still long; however, halicin is not just another antibiotic. The compound has several properties that make it a unique candidate. For instance, it not only kills but shreds bacterial cells, making it harder for bacteria to become resistant.
Moreover, halicin has also shown potential to combat other diseases such as tuberculosis and cancer. Researchers are now exploring the full range of possibilities halicin might offer and are optimistic that the AI approach can be used to discover more new antibiotics.
Conclusion
The link between AI and healthcare has been growing over recent years, transforming how we approach diagnosis, screening, and treatment. Now, AI has helped discover a new antibiotic to combat antibiotic-resistant bacteria, offering new hope to curb the rising threat to human health. The use of AI in this process has the potential to revolutionize the drug discovery process and save lives.
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