Understanding Evenity Prescribing Information: A Comprehensive Guide for Medical Professionals

If you’re a medical professional seeking to prescribe Evenity or assist patients who require the medication, it’s essential to have a thorough understanding of its prescribing information.

Introduction

Evenity is an injectable medication approved by the FDA in 2019 to treat osteoporosis in postmenopausal women at high risk of fracture. This medication is a combination of two monoclonal antibodies that block a protein called sclerostin, which inhibits bone formation. Evenity works by increasing bone formation and decreasing bone resorption, which ultimately increases bone mass and reduces the risk of fracture.

How to Prescribe Evenity

Evenity is administered as two injections of 105 mg each once a month. However, the prescribing information for Evenity contains a boxed warning regarding the risk of cardiovascular events such as heart attacks and strokes. Therefore, before prescribing Evenity, medical professionals should assess the patient’s cardiovascular risk and only prescribe if the patient’s benefits outweigh the potential risks.

Monitoring Osteoporosis with Evenity

Evenity’s prescribing information also recommends monitoring patients for signs of hypersensitivity reactions, including anaphylaxis, angioedema, and urticaria. Additionally, medical professionals should measure serum calcium levels before each injection of Evenity and monitor patients for signs of hypercalcemia, including hypercalciuria and nephrolithiasis.

Common Side Effects of Evenity

The most commonly reported side effects of Evenity include joint pain, headache, and injection site reactions such as pain, swelling, and itching. Medical professionals should inform patients of these potential side effects and instruct them to report any adverse reactions promptly.

Conclusion

Evenity is a novel medication that offers new options for medical professionals to help patients at high risk of fracture due to osteoporosis. Its prescribing information contains vital information about the risks and benefits of the medication, including monitoring for cardiovascular events, assessing patient risks before prescribing, monitoring for hypersensitivity reactions, and measuring serum calcium levels. By understanding Evenity’s prescribing information, medical professionals can better prescribe the medication and monitor their patients for potential adverse effects.