Understanding Valbenazine Prescribing Information: A Guide for Patients and Healthcare Providers
Valbenazine is a medication used for the treatment of tardive dyskinesia. It has gained popularity in recent years due to its effectiveness in the management of symptoms associated with this condition. However, it is essential to understand its prescribing information to ensure safe and appropriate use. In this article, we will guide patients and healthcare providers on understanding Valbenazine’s prescribing information.
How Does Valbenazine Work?
Valbenazine works by regulating the levels of dopamine in the brain. Dopamine is a neurotransmitter that plays a crucial role in movement control. In patients with tardive dyskinesia, there is an imbalance of dopamine levels, leading to involuntary movements such as grimacing and tongue protrusion. Valbenazine targets the specific pathway responsible for this imbalance, reducing the severity and frequency of these involuntary movements.
Dosage and Administration
Valbenazine is available as a capsule in strengths of 40mg and 80mg. The dosage will depend on various factors such as age, weight, and medical history. The recommended starting dose is 40mg once a day, and the dose can be increased to 80mg once a day after one week if necessary. Valbenazine capsules should be taken with food to increase its absorption rate.
Side Effects
Like every medication, Valbenazine comes with some side effects. The most common side effects include drowsiness, dry mouth, and restlessness. However, if these side effects persist or worsen, patients should seek medical attention. Valbenazine may also cause a rare but severe side effect known as tardive dysphoria, characterized by severe depression and suicidal thoughts. Patients and healthcare providers should be vigilant in monitoring these symptoms.
Warnings and Precautions
Valbenazine is contraindicated in patients with a history of neuroleptic malignant syndrome, hypersensitivity to the medication, and QT prolongation. It should be used with caution in patients with severe hepatic impairment and those taking medications that prolong QT interval. Patients with a history of depression or suicidal tendencies should also be monitored closely while taking Valbenazine.
Conclusion
Valbenazine is an effective medication for the treatment of tardive dyskinesia. However, patients and healthcare providers should be well-informed of its prescribing information before using it. The medication’s dosage and administration, side effects, and warnings and precautions should be carefully considered. Patients should consult their healthcare provider before starting or stopping Valbenazine and report any adverse effects immediately. By understanding Valbenazine’s prescribing information, patients and healthcare providers can ensure safe and appropriate use of the medication.
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